| No | Publication Year |
Document Type | Article Title | Source | Author | DOI |
|---|---|---|---|---|---|---|
| 38 | 2023 | Meeting Abstract | Th1/17 polarization and potential treatment by an anti-interferon-γ DNA aptamer in Hunner-type interstitial cystitis | American Urological Association (AUA) 2023 Annual Meeting | Yoshiyuki Akiyama, Kaori Harada, Karl Kreder, Michael O’Donnell, Daichi Maeda, Susumu Muto, Haruki Kume, Yukio Homma, Yi Luo | 10.1097/JU.0000000000003229.07 |
| 37 | 2023 | Meeting Abstract | Th1/17 polarization and potential treatment by an anti-interferon-γ DNA aptamer in Hunner-type interstitial cystitis | The 110th Annual Meeting of The Japanese Urological Association (JUA) | Yoshiyuki Akiyama | |
| 36 | 2022 | Meeting Abstract | 人工塩基導入 DNA アプタマーを活用した次世代アフェレーシス開発の試み | The 43rd Annual Meeting of the Japanese Society for Apheresis | Kensuke Owari, Miyuki Hori, Kazunobu Futami, Haishun Piao, Gen Watanabe, Chizuko Koseki | |
| 35 | 2022 | Meeting Abstract | VEGF165 に対する人工塩基 Ds を含む DNA アプタマーの NMR 解析 | The 61st Annual Meeting of the NMR Society of Japan | Tomomi Nagahama, Tatsuhiko Someya, Taiichi Sakamoto | |
| 34 | 2022 | Article | Development of a novel aptamer blocking the interaction between the VWF A1 domain and platelet GP Ib for the treatment of arterial thrombosis | Rinsho Ketsueki | Masanori Matsumoto, Kaori Harada | 10.11406/rinketsu.63.393 |
| 33 | 2021 | Meeting Abstract | Development of novel aptamer blocking the interaction between VWF A1 domain and platelet GP Ib for the treatment of arterial thrombosis | The 83rd Annual Meeting of Japanese Society of Hematology(JSH) | Masanori Matsumoto | |
| 32 | 2021 | Meeting Abstract | Exploring the potential of the novel IFNγ aptamer TAGX-0003 as a treatment for alopecia areata in pre-clinical models | 50th Annual European Society for Dermatological Research (ESDR) Meeting | Markus Fehrholz, Kaori Harada, Ilaria Piccini, Amos Gilhar, Susumu Muto, Marta Bertolini | 10.1016/j.jid.2021.08.024 |
| 31 | 2021 | Meeting Abstract | NMR Analysis of Interaction between an ssDNA Aptamer Containing Artificial Base Ds and VEGF165 | The 60th Annual Meeting of the NMR Society of Japan | Tomomi Nagahama, Tatsuhiko Someya, Susumu Muto, Taiichi Sakamoto | |
| 30 | 2021 | Meeting Abstract | Novel IFNγ aptamer TAGX-0003 protected hair follicles from immune privilege collapse and reversed alopecia areata like phenotype in humanized mouse model. | 2021 Society for Investigative Dermatology (SID) Virtual Meeting | Kaori Harada, Markus Fehrholz, Ilaria Piccini, Amos Gilhar, Marta Bertolini, Susumu Muto | 10.1016/j.jid.2021.07.119 |
| 29 | 2020 | Meeting Abstract | 線維芽細胞増殖因子受容体を標的とした 人工塩基含有DNAアゴニストの開発 | 10th CSJ Chemistry Festa | Hayata, Yuri; Futami, Kazunobu; Ueki, Ryosuke; Sando, Shinsuke | |
| 28 | 2020 | Meeting Abstract | Intradermal permeability of DNA aptamer through transdermal administration using Ionic Liquid | The 35th Annual Meeting of The Academy of Pharmaceutical Science and Technology, Japan (APSTJ) | Yukari Ikeda, Yuuki Takashima, Hisako Ibaraki, Yasunori Iwao, Kaori Harada, Susumu Muto | |
| 27 | 2020 | Meeting Abstract | Improvement of skin penetration of DNA aptamer using ionic liquid | The 36th Annual Meeting of the Japan Society of Drug Delivery System | Ikeda, Yukari; Takashima, Yuki; Ibaraki, Hisako; Iwao, Yasunori; Harada, Kaori; Muto, Susumu | |
| 26 | 2020 | Article | Oligonucleotide aptamers: therapeutics and clinical applications | Japanese Journal of Thrombosis and Hemostasis | Akinori Mochizuki | 10.2491/jjsth.31.66 |
| 25 | 2020 | Article | Novel aptamer to von Willebrand factor A1 domain (TAGX-0004) shows total inhibition of thrombus formation superior to ARC1779 and comparable to caplacizumab | HAEMATOLOGICA | Sakai, Kazuya; Someya, Tatsuhiko; Harada, Kaori; Yagi, Hideo; Matsui, Taei; Matsumoto, Masanori | 10.3324/haematol.2019.235549 |
| 24 | 2019 | Article | Genetic Alphabet Expansion Provides Versatile Specificities and Activities of Unnatural-Base DNA Aptamers Targeting Cancer Cells | MOLECULAR THERAPY-NUCLEIC ACIDS | Futami, Kazunobu; Kimoto, Michiko; Lim, Yun Wei Shermane; Hirao, Ichiro | 10.1016/j.omtn.2018.11.011 |
| 23 | 2018 | Meeting Abstract | Inhibitory effect of novel DNA aptamer for von Willebrand factor on platelet thrombosis formation | The 80th Annual Meeting of the Japanese Society of Hematology (JSH) | Kazuya Sakai, Hideo Yagi, Masaki Hayakawa, Kaori Harada, Tatsuhiko Someya, Yoshihiro Fujimura, Masanori Matsumoto | |
| 22 | 2018 | Meeting Abstract | New treatment modalities for thrombotic thrombocytopenic purpura | The 10th Congress of the Asian-Pacific Society on Thrombosis and Hemostasis (APSTH) | Masanori Matsumoto | |
| 21 | 2018 | Meeting Abstract | Inhibitory Effect of a Novel DNA Aptamer with Artificial Nucleic Bases for Von Willebrand Factor A1 Domain on Platelet Thrombosis Formation | 60th American Society of Hematology (ASH) Annual Meeting and Exposition | Sakai, Kazuya; Yagi, Hideo; Hayakawa, Masaki; Someya, Tatsuhiko; Harada, Kaori; Matsumoto, Masanori | 10.1182/blood-2018-99-113948 |
| 20 | 2017 | Article | High-Affinity DNA Aptamer Generation Targeting von Willebrand Factor A1-Domain by Genetic Alphabet Expansion for Systematic Evolution of Ligands by Exponential Enrichment Using Two Types of Libraries Composed of Five Different Bases | JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | Matsunaga, Ken-ichiro; Kimoto, Michiko; Hirao, Ichiro | 10.1021/jacs.6b10767 |
| 19 | 2016 | Article | Post-ExSELEX stabilization of an unnatural-base DNA aptamer targeting VEGF(165) toward pharmaceutical applications | NUCLEIC ACIDS RESEARCH | Kimoto, Michiko; Nakamura, Mana; Hirao, Ichiro | 10.1093/nar/gkw619 |
| 18 | 2015 | Article | Architecture of high-affinity unnatural-base DNA aptamers toward pharmaceutical applications | SCIENTIFIC REPORTS | Matsunaga, Ken-ichiro; Kimoto, Michiko; Hanson, Charlotte; Sanford, Michael; Young, Howard A.; Hirao, Ichiro | 10.1038/srep18478 |
| 17 | 2015 | Article | Site-specific labeling of RNA by combining genetic alphabet expansion transcription and copper-free click chemistry | NUCLEIC ACIDS RESEARCH | Someya, Tatsuhiko; Ando, Ami; Kimoto, Michiko; Hirao, Ichiro | 10.1093/nar/gkv638 |
| 16 | 2014 | Meeting Abstract | Inhibiting cytokine activity - The use of modified DNA aptamers as an alternative to neutralizing antibodies | CYTOKINE | Young, Howard A.; Hanson, Charlotte; Sanford, Michael; Matsunaga, Ken-ichiro; Kimoto, Michiko; Hirao, Ichiro | 10.1016/j.cyto.2014.07.215 |
| 15 | 2013 | Review | Site-Specific Functional Labeling of Nucleic Acids by In Vitro Replication and Transcription using Unnatural Base Pair Systems | ISRAEL JOURNAL OF CHEMISTRY | Kimoto, Michiko; Hikida, Yasushi; Hirao, Ichiro | 10.1002/ijch.201300013 |
| 14 | 2013 | Article | Generation of high-affinity DNA aptamers using an expanded genetic alphabet | NATURE BIOTECHNOLOGY | Kimoto, Michiko; Yamashige, Rie; Matsunaga, Ken-ichiro; Yokoyama, Shigeyuki; Hirao, Ichiro | 10.1038/nbt.2556 |
| 13 | 2012 | Review | Natural versus Artificial Creation of Base Pairs in DNA: Origin of Nucleobases from the Perspectives of Unnatural Base Pair Studies | ACCOUNTS OF CHEMICAL RESEARCH | Hirao, Ichiro; Kimoto, Michiko; Yamashige, Rie | 10.1021/ar200257x |
| 12 | 2012 | Review | Unnatural base pair systems toward the expansion of the genetic alphabet in the central dogma | PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES | Hirao, Ichiro; Kimoto, Michiko | 10.2183/pjab.88.345 |
| 11 | 2012 | Article | Site-Specific Incorporation of Functional Components into RNA by an Unnatural Base Pair Transcription System | MOLECULES | Morohashi, Nobuyuki; Kimoto, Michiko; Sato, Akira; Kawai, Rie; Hirao, Ichiro | 10.3390/molecules17032855 |
| 10 | 2012 | Article | Highly specific unnatural base pair systems as a third base pair for PCR amplification | NUCLEIC ACIDS RESEARCH | Yamashige, Rie; Kimoto, Michiko; Takezawa, Yusuke; Sato, Akira; Mitsui, Tsuneo; Yokoyama, Shigeyuki; Hirao, Ichiro | 10.1093/nar/gkr1068 |
| 9 | 2012 | Article | Site-specific functionalization of RNA molecules by an unnatural base pair transcription system via click chemistry | CHEMICAL COMMUNICATIONS | Ishizuka, Takumi; Kimoto, Michiko; Sato, Akira; Hirao, Ichiro | 10.1039/c2cc36293g |
| 8 | 2011 | Review | Unnatural base pair systems for sensing and diagnostic applications | EXPERT REVIEW OF MOLECULAR DIAGNOSTICS | Kimoto, Michiko; Cox, Robert Sidney, III; Hirao, Ichiro | 10.1586/ERM.11.5 |
| 7 | 2011 | Article | Monitoring the site-specific incorporation of dual fluorophore-quencher base analogues for target DNA detection by an unnatural base pair system | ORGANIC & BIOMOLECULAR CHEMISTRY | Yamashige, Rie; Kimoto, Michiko; Mitsui, Tsuneo; Yokoyama, Shigeyuki; Hirao, Ichiro | 10.1039/c1ob06118f |
| 6 | 2010 | Article | A New Unnatural Base Pair System between Fluorophore and Quencher Base Analogues for Nucleic Acid-Based Imaging Technology | JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | Kimoto, Michiko; Mitsui, Tsuneo; Yamashige, Rie; Sato, Akira; Yokoyama, Shigeyuki; Hirao, Ichiro | 10.1021/ja1072383 |
| 5 | 2010 | Article | A Unique Fluorescent Base Analogue for the Expansion of the Genetic Alphabet | JOURNAL OF THE AMERICAN CHEMICAL SOCIETY | Kimoto, Michiko; Mitsui, Tsuneo; Yokoyama, Shigeyuki; Hirao, Ichiro | 10.1021/ja100806c |
| 4 | 2010 | Article | Site-specific fluorescent probing of RNA molecules by unnatural base-pair transcription for local structural conformation analysis | NATURE PROTOCOLS | Hikida, Yasushi; Kimoto, Michiko; Yokoyama, Shigeyuki; Hirao, Ichiro | 10.1038/nprot.2010.77 |
| 3 | 2009 | Meeting Abstract | Development of unnatural base pair systems toward new biotechnology | ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | Hirao, Ichiro | |
| 2 | 2009 | Meeting Abstract | Efficient PCR amplification functionalization by an unnatural base pair system | ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY | Kim, Michiko; Kawai, Rie; Mitsui, Tsuneo; Yokoyama, Shigeyuki; Hirao, Ichiro | |
| 1 | 2009 | Article | An unnatural base pair system for efficient PCR amplification and functionalization of DNA molecules | NUCLEIC ACIDS RESEARCH | Kimoto, Michiko; Kawai, Rie; Mitsui, Tsuneo; Yokoyama, Shigeyuki; Hirao, Ichiro | 10.1093/nar/gkn956 |
